HAGH is a member of the glyoxalase family and a thiolesterase which hydrolyses S-lactoyl-glutathione to reduced glutathione and D-lactate. This protein is a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73 and serves as a pro-survival factor of the p53 family. It exists only as a monomer and binds two zinc ions per subunit. Recombinant human HAGH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
序列
重组人HAGH蛋白产品，又称Hydroxyacylglutathione hydrolase, GLO, GLX2, Glyoxalase II, HAGH1.其对应NCBI基因号为3029，对应Accession号为Q16775.
来源宿主
提供的【HAGH】重组人HAGH产品的来源为大肠杆菌重组表达.
溶解建议
重组人HAGH产品为液体即用型，其溶液组成为：0.5 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
