Glycoprotein that belongs to a family which takes part in the activation and regulation of the MMP-activity. Forms a non-covalent stoichiometric complex with latent and active MMP's. Inhibits the activities of MMP-1, MMP-2, MMP-12 and transin.
序列
天然人成纤维细胞基质金属蛋白酶抑制物-2蛋白产品,又称Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2).其对应NCBI基因号为7077,对应Accession号为P16035.
来源宿主
提供的【TIMP2】天然人成纤维细胞基质金属蛋白酶抑制物-2产品的来源为人成纤维细胞中分离.
溶解建议
天然人成纤维细胞基质金属蛋白酶抑制物-2产品为液体即用型,其溶液组成为:In 50 mM Tris-HCl, pH 7; 200 mM NaCl; 5 mM CaCl₂; 1 uM ZnCl₂; 0.05% Brij 35; 0,05% NaN₃