UNC5B is a receptor for the netrin family of guidance molecules. It was identified as a mediator of the repulsive response in neurons and it is the only known netrin receptor with prominent endothelial expression. It has an important role in angiogenesis signaling.
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人源细胞表达的重组人UNC5B蛋白产品,又称Netrin Receptor UNC5B; UNC5H2; Protein Unc-5 Homolog 2; Protein Unc-5 Homolog B; p53-regulated Receptor for Death and Life Protein 1.其对应NCBI基因号为219699,对应Accession号为Q8IZJ1.