Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the ‘calreticulin/calnexin cycle’ that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.
序列
重组人钙网蛋白蛋白产品，又称CRP55; Calregulin; Endoplasmic Reticulum Resident Protein 60; ERp60; grp60.其对应NCBI基因号为811，对应Accession号为P27797.
来源宿主
提供的【Calreticulin】重组人钙网蛋白产品的来源为大肠杆菌重组表达.
溶解建议
重组人钙网蛋白产品为液体即用型，其溶液组成为：0.2 um-filtered solution in 55 mM Tris-Cl, pH 8.2, containing 150 mM NaCl.
