Retinol binding protein 4 (RBP4; RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
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人源细胞表达的重组大鼠视黄醇结合蛋白4蛋白产品,又称Retinol Binding Protein 4, Plasma retinol-binding protein, PRBP, RBP.其对应NCBI基因号为25703,对应Accession号为P04916.