FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
序列
重组小鼠FTO蛋白产品，又称Fat Mass and Obesity-associated Protein; FATSO.其对应NCBI基因号为26383，对应Accession号为Q8BGW1.
来源宿主
提供的【FTO】重组小鼠FTO产品的来源为大肠杆菌重组表达.
溶解建议
重组小鼠FTO产品为液体即用型，其溶液组成为：0.5 mg/ml of 0.2 um-filtered solution in 55 mM Tris-Cl, pH 8.2 containing 150 mM NaCl.
