- 中文名称
【SIRPA】人源细胞表达重组人CD172A / SIRP
- 英文名字
- Human CellExp™ CD172A / SIRP, human recombinant
- 供应商
- Biovision
- 产品货号
- 7506-10
- 产品报价
- ￥已停产
- 产品说明书
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- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868.
- 产品新闻
- 背景资料
- Tyrosine-protein phosphatase non-receptor type substrate 1 (SHPS1) is also known as CD172 antigen-like family member A (CD172a), Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha (SIRPA or SIRP alpha) or p84, is a member of the SIRP family, and also belongs to the immunoglobulin superfamily. SIRP alpha is Ubiquitous and highly expressed in brain. SIRPA / CD172a is immunoglobulin-like cell surface receptor for CD47 and acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRPA / SHPS-1 supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment and may play a key role in intracellular signaling during synaptogenesis and in synaptic function By similarity. SIRPA / MyD1 involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin and mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.
- 序列
- 人源细胞表达重组人CD172A/SIRP又称SHPS1, SIRPA, CD172A, BIT, MFR, MYD1, P84, PTPNS1.其对应NCBI基因号为140885，对应Accession号为P78324.
- 来源宿主
- 提供的【SIRPA】人源细胞表达重组人CD172A/SIRP蛋白产品来源为人胚肾HEK 293细胞中重组表达.
- 溶解建议
- 提供的人源细胞表达重组人CD172A/SIRP产品为固体冻干粉形式.开盖前，请先离心.溶解于PBS缓冲液中, pH 7.4. 请勿涡旋！
- 保存建议
- 艾美捷推荐冰袋运输【SIRPA】人源细胞表达重组人CD172A/SIRP产品.我们建议您收到该产品后将其置于-20°C保存.产品有效期为收到产品后12个月.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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