- 中文名称
【LEPR】人源细胞表达的重组人LEPR / CD295(10微克)
- 英文名字
- Human CellExp LEPR/CD295, human recombinant
- 供应商
- Biovision
- 产品货号
- 7497-10
- 产品报价
- ¥已停产

- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻

- 背景资料
- Leptin receptor (LEPR), also known as LEP-R, cluster of differentiation 295 (CD295), OB-R and B219, is a single-transmembrane-domain receptor of the gp130 family of cytokine receptors. Leptin receptor exists as homodimer and binds Leptin with high affinity, thus mediates the biological function of the adipocyte-specific hormone Leptin. LEPR is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this protein have been associated with obesity and pituitary dysfunction. Interaction of leptin and leptin receptor is crucial for body weight and bone mass regulation in mammals through hypothalamic effects on satiety and energy expenditure. Meanwhile, research data supports a leptin receptor activation model based on ligand-induced conformational changes.
- 序列
- 人源细胞表达的重组人LEPR/CD295蛋白产品,又称LEPR, CD295, DKFZp686B1731, LEP-R, OB-R, OBR, Leptin receptor.其对应NCBI基因号为3953,对应Accession号为P48357.
- 来源宿主
- 提供的【LEPR】人源细胞表达的重组人LEPR/CD295产品的来源为人胚肾HEK293细胞重组表达重组表达.
- 溶解建议
- 人源细胞表达的重组人LEPR/CD295产品请按照说明书建议进行溶解操作:Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
- 保存建议
- 在您收到艾美捷发出的【LEPR】人源细胞表达的重组人LEPR/CD295产品后,建议将其置于-20°C保存.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的Leader,BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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