- 中文名称
【KITLG】人源细胞表达的重组小鼠KITLG /干细胞因子(10 ug)
- 英文名字
- Human CellExp KITLG /SCF, mouse recombinant
- 供应商
- Biovision
- 产品货号
- 7483-10
- 产品报价
- ¥已停产

- 产品说明书
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- 产品新闻

- 背景资料
- Kit ligand (KITLG) also known as stem cell factor (SCF), mast cell growth factor (MGF), steel factor (SF), which belongs to the SCF family, and is a widely expressed 28 - 40 kDa type I transmembrane glycoprotein. KITLG is the ligand for the receptor-type protein-tyrosine kinase KIT. SCF / MGF plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG / SCF binding can activate several signaling pathways. KITLG / SF Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG / SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG / SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG / SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1, 4, 5 - triphosphate. KITLG / SCF acts synergistically with other cytokines, probably interleukins.
- 序列
- 人源细胞表达的重组小鼠KITLG/干细胞因子蛋白产品,又称KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7, KL.其对应NCBI基因号为17311,对应Accession号为P20826.
- 来源宿主
- 提供的【KITLG】人源细胞表达的重组小鼠KITLG/干细胞因子产品的来源为人胚肾HEK293细胞重组表达重组表达.
- 溶解建议
- 人源细胞表达的重组小鼠KITLG/干细胞因子产品请按照说明书建议进行溶解操作:Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
- 保存建议
- 在您收到艾美捷发出的【KITLG】人源细胞表达的重组小鼠KITLG/干细胞因子产品后,建议将其置于-20°C保存.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的Leader,BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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