Fructose bisphosphate aldolase A, also known as Aldolase A is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. It is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Deficiency has been associated with myopathy and hemolytic anemia. Recombinant human Aldolase A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
序列
重组人Aldolase A蛋白产品,又称Fructose bisphosphate Aldolase A, ALDOA, ALDA, GSD12 .其对应NCBI基因号为226,对应Accession号为P04075.
来源宿主
提供的【Aldolase A】重组人Aldolase A产品的来源为大肠杆菌重组表达.
溶解建议
重组人Aldolase A产品为液体即用型,其溶液组成为:1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 100 mM NaCl and 10% glycerol.