中文名称

【ApoA4】天然人血浆载脂蛋白AIV（50微克）

英文名字

Apolipoprotein AIV, Human Plasma

供应商

Biovision

产品货号

7282-50

产品报价

￥已停产

产品说明书

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产品新闻

背景资料

Apolipoprotein AIV (Apo AIV) is a glycoprotein synthesized by the human intestine. Synthesis appears to be stimulated by the absorption of high density lipoproteins that are rich in triglycerides rather than by the uptake or re-esterification of fatty acids. The formation of chylomicrons acts as a signal for the induction of Apo AIV synthesis a signal enhanced by a factor from the ileum, probably PYY. Apo AIV alters the activity of the key enzymes (LPL and LCAT) of lipoprotein metabolism and cholesterol efflux from extra hepatic tissues. Also, since stimulation of intestinal synthesis and secretion by lipid absorption are rapid, Apo AIV likely plays a role in the short-term regulation of food intake. Other evidence suggests involvement in the long-term regulation of both food intake and body weight. Chronic ingestion of high-fat diet blunts the intestinal Apo AIV response to lipid feeding and, consequently, may explain why the chronic ingestion of a high-fat diet predisposes both animals and humans to obesity. It is required for efficient activation of lipoprotein lipase by ApoC-II and is a potent activator of LCAT. Apo AIV is an amphipathic protein that can emulsify lipids and has been linked to protective roles against cardiovascular disease and obesity.

序列

天然人血浆载脂蛋白AIV蛋白产品，又称Apolipoprotein A-IV, apo AIV, Apo-AIV, ApoA-IV.其对应NCBI基因号为337，对应Accession号为P06727.

来源宿主

提供的【ApoA4】天然人血浆载脂蛋白AIV产品的来源为人血浆中分离.

溶解建议

该【ApoA4】天然人血浆载脂蛋白AIV（50微克）Apolipoprotein AIV, Human Plasma产品的溶解建议详情请查阅产品说明书。

保存建议

在您收到艾美捷发出的【ApoA4】天然人血浆载脂蛋白AIV产品后，建议将其置于-80°C保存.

其他

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

注意

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