Baicalein is a flavonoid originally isolated from the roots of Scutellaria baicalensis Georgi. Several different functions of baicalein have been reported. Platelet 12-lipoxygenase is inhibited by baicalein with an ID50 value of 0.12 uM， with minimal inhibition of platelet cyclooxygenase-1 （IC50 = 0.83 mM）. Baicalein inhibits lipid peroxidation， as assessed by production of TBARS， with an IC50 value of 5 uM. In addition to these effects， baicalein may play a role in apoptosis， as the compound inhibits cell growth of three human hepatocellular carcinoma cell lines with IC50 values ranging from 17-70 ug/ml.
产品描述
A flavonoid originally isolated from the roots of Scutellaria baicalensis Georg； inhibits platelet 12-LO with an ID50 value of 0.12 uM， with minimal inhibition of platelet COX-1 （IC50 = 0.83 mM）； inhibits lipid peroxidation， as assessed by production of TBARS， with an IC50 value of 5 uM
