JMJD2c belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2c specifically demethylates the trimethylated K9 and K36 of histone H3. It is not able to demethylate K4,K27 and K36 of histone H3,K20 of histone H4,or the mono- and dimethylated H3K9 and H3K36.
应用类型
Western Blot: 1:1000, ELISA: 1:50.
免疫原
Polyclonal antibody raised in rabbit against human JMJD2c (Jumonji Domain containing 2c), using a KLH-conjugated synthetic peptide containing an amino acid sequence from the central part of the protein.