Dnmt2 belongs to the family of DNA cytosine methyltransferases. Dnmt2,however,lacks the large N-terminal regulatory domain common to other eukaryotic methyltransferases and does not methylate CpG in genomic DNA. Instead,it specifically methylates cytosine 38 in the anticodon loop of Asp transfer RNA.
应用类型
Western Blot: 1:1000, ELISA: 1:100 – 1:1000
免疫原
Polyclonal antibody raised in rabbit against mouse Dnmt2 (DNA methyltransferase 2), using a KLH conjugated synthetic peptide containing an amino acid sequence from the N-terminal part of the protein.