CD34 is a heavily glycosylated,105-120 kDa transmembrane glycoprotein expressed on hematopoietic progenitor cells,vascular endothelial cells and some fibroblasts. The CD34 cytoplasmic domain is a target for phosphorylation by activated protein kinase C,suggesting a role for CD34 in signal transduction. CD34 may also play a role in adhesion of certain antigens to endothelium.
应用类型
WB: 1:1000, FC: 1:10 – 1:50.
免疫原
This CD34 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 185-212 amino acids from the Central region of human