Fructose 1，6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1，6-bisphosphate. Fructose 1，6-bisphosphate aldolase exists as three forms，the muscle-specific Aldolase A，the liver-specific aldolase B，and the brain-specific aldolase C. Aldolase A，B，and C arose from a common ancestral gene，from which aldolase B first diverged. Aldolase A is one of the most highly conserved enzymes known，with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.
应用类型
Western blot: ~1:1000.
免疫原
Purified His-tagged ALDOC protein was used to produce this monoclonal antibody.
来源宿主
小鼠
反应性
经检测验证，可与人和小鼠 种属来源的Aldolase C （ALDOC）抗体（C末端） 克隆号859CT9.5.3蛋白发生免疫反应.
保存建议
提供的Aldolase C （ALDOC）抗体（C末端） 克隆号859CT9.5.3产品为无色溶液形式，含有100 ul抗体.该产品浓度为与批次相关，溶解于包含有0.09% （W/V） 叠氮化钠的PBS缓冲液中.请在收到该Aldolase C （ALDOC）抗体（C末端） 克隆号859CT9.5.3产品后，将其置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
