Apolipoproteins are plasma lipoproteins that function as transporters of lipids and cholesterol in the circulatory system. The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels,a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5.
应用类型
Western blot: ~1:1000, IHC: ~1:10-1:50.
免疫原
This APOA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-52 amino acids from the N-terminal region of human APOA5.