The TTRAP/TDP2 gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40，tumor necrosis factor （TNF） receptor-75 and TNF receptor associated factors （TRAFs），and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease，which is involved in both DNA repair and the activation of transcription factors.
应用类型
Western blot: ~0.5 ug/ml， ELISA: ~1:62，500 dilution， IHC.
免疫原
Antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of human TTRAP/TDP2.
