Receptor-induced calcium signalling relies on inositol-1,4,5-triphosphate receptors. These receptors can be blocked by the cell-permeable antagonist 2-APB. In fura-loaded DDT1MF-2 cells, 75 uM 2-APB completely ablates the thapsigargin-induced calcium transients that are also antagonized by xestospongin C.
产品描述
Receptor-induced calcium signalling relies on 1,4,5-IP3 receptors.{11002} These receptors can be blocked by the cell-permeable antagonist 2-APB. In fura-loaded DDT1MF-2 cells, 75 uM 2-APB completely ablates the thapsigargin-induced calcium transients that are also antagonized by xestospongin C.{9842}