- 中文名称
【UBE2K】重组人泛素蛋白连接酶UBE2K（3 nmol）
- 英文名字
- Human recombinant UBE2K
- 供应商
- Biovision
- 产品货号
- 6432-3
- 产品报价
- ￥已停产
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868.
- 产品新闻
- 背景资料
- UBE2K, also known as UbcH1 or E2-25K, is an E2 (ubiquitin conjugating enzyme) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E3 enzymes. Once an E1 is carrying an activated ubiquitin in a ubiquitin-E1 thiolester complex, this activated ubiquitin is transferred to the active site cysteine of the E2 to form a ubiquitin-E2 thiolester complex. With the aid of an E3, the activated ubiquitin is then targeted to a specific substrate lysine. UBE2K is a biochemically important E2 due to its ability to form free K48-linked polyubiquitin chains in solution in the absence of an E3. This ability is attributed to UbcH1 possessing a C-terminal UBA domain, in addition to its E2 catalytic domain. UBE2K takes part in many cellular processes such as selective protein degradation, DNA repair, cell cycle control, and sporulation. In addition, UBE2K is involved in Alzheimer's disease, Huntington's disease and antigen processing through its interaction with amyloid-β, Huntington, and MHC-heavy chain proteins.
- 序列
- 重组人泛素蛋白连接酶UBE2K蛋白产品，又称HIP2, Huntingtin Interacting protein 2, HYPG, Ubiquitin-conjugating enzyme E2-25K kDa, Ubiquitin-protein ligase, Ubiquitin carrier protein, LIG, HIP-2, E2 (25K), DKFZp686J24237, EC 6.3.2.19.其对应NCBI基因号为3093，对应Accession号为P61086.
- 来源宿主
- 提供的【UBE2K】重组人泛素蛋白连接酶UBE2K产品的来源为重组表达.
- 溶解建议
- 重组人泛素蛋白连接酶UBE2K产品为液体即用型，其溶液组成为：75 uL of a 40 uM solution (3 nmoles) in TBS.
- 保存建议
- 在您收到艾美捷发出的【UBE2K】重组人泛素蛋白连接酶UBE2K产品后，建议将其置于-80°C保存.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
-
