Cyclophilin D is a member of peptidyl-propyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins and thus their formation. Cyclophilin D is also a mitochondrial matrix protein, which plays a decisive role in mitochondrial permeability transition. It can bind to the immunosuppressant cyclosporine A and its overexpression suppresses the apoptosis in cancer cells.
序列
重组人亲环蛋白 D 蛋白产品,又称Peptidylprolyl isomerase D, PPID, CYPD, CYP-40.其对应NCBI基因号为5481,对应Accession号为Q08752.
来源宿主
提供的【Cyclophilin D 】重组人亲环蛋白 D 产品的来源为大肠杆菌重组表达.
溶解建议
重组人亲环蛋白 D 产品为液体即用型,其溶液组成为:1 mg/ml solution in PBS (pH 7.4) containing 10% glycerol.
保存建议
在您收到艾美捷发出的【Cyclophilin D 】重组人亲环蛋白 D 产品后,建议将其置于-80°C保存.