EZH1 is a human homolog of the Drosophila gene Enhancer of zeste E(z),a member of the polycomb group of transcriptional repressors. In mice,EZH1 is a regulator of homeotic gene expression implicated in the assembly of repressive protein complexes in chromatin. The strong sequence conservation between species suggests potential role for EZH1 in human development as a transcriptional regulator and as a component of protein complexes that stably maintain heterochromatin.
应用类型
Western blot: 1-2 ug/ml. However, the optimal conditions should be determined individually.