- 中文名称
D-myo-Inositol-1,3,4-triphosphate (sodium salt) (5 mg)
- 英文名字
- Ins(1,3,4)-P3 (sodium salt)|1,3,4-IP3 (sodium salt), D-myo-Inositol-1,3,4-triphosphate, D-myo-inositol-1,3,4-tris(dihydrogen phosphate), trisodium salt
- 供应商
- Cayman
- 产品货号
- 60972-5
- 产品报价
- ￥19110/5 mg
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- The inositol phosphates play a critical role as small, soluble second messengers in transmission of cellular signals. D-myo-Inositol-1,3,4-triphosphate (Ins(1,3,4)-P3) is one of several different inositol oligophosphate isomers implicated in signal transduction. Ins(1,3,4)-P3 acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase the cellular level of Ins(3,4,5,6)-P4 and thus inhibit calcium-activated chloride channels. The levels of Ins(1,3,4)-P3 are in turn regulated by the levels of cytosolic free calcium. The receptor-mediated activation of phospholipase C (PLC) can be seen as the initiating event in this cascade, since PLC generates Ins(1,4,5)-P3 which releases calcium from intracellular storage reservoirs, leading to a dramatic but transient increase in the cytosolic concentration of free calcium.
- 产品描述
- A member of the InsP family of small, soluble second messengers; inhibits Ins(3,4,5,6)P4 kinase activity to increase the cellular level of Ins(3,4,5,6)P4
- 产品形式
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
-
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