Synaptonemal complex protein 3 (Scp3) is a component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. These proteins are required for centromere pairing during meiosis in male germ cells. It is required for normal meiosis during spermatogenesis and male fertility but plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Anti-Scp3 Antibody is useful for researchers interested in Meiosis, Mitotic Cell Cycle, and fertility.
应用类型
ELISA,Immunohistochemistry,Western Blot,
免疫原
Anti-Scp3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a near N-terminal region of mouse Scp3 conjugated to Keyhole Limpet Hemocyanin (KLH).
来源宿主
Rabbit
反应性
该【干冰】Anti-Scp3 (RABBIT) Antibody - 600-401-MP9的详细信息查看Synaptonemal complex protein 3 (Scp3) is a component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. These proteins are required for centromere pairing during meiosis in male germ cells. It is required for normal meiosis during spermatogenesis and male fertility but plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Anti-Scp3 Antibody is useful for researchers interested in Meiosis, Mitotic Cell Cycle, and fertility.提供的产品说明书。
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
