HDAC4 antibody belongs to class II of the histone deacetylase/acuc/apha family. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC4 represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. Anti-HDAC4 is ideal for investigators interested in Stem Cell , Cardiovascular , and Epigenetics and Nuclear Signaling research.
应用类型
ELISA,Western Blot,
免疫原
HDAC4 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region surrounding 150-200aa of mouse HDAC4.
来源宿主
Rabbit
反应性
H. sapiens (Human)
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.