Periostin Antibody detects Periostin protein. Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium. Anti-Periostin Antibody is ideal for investigators involved in Cancer and Cardiovascular research.
应用类型
Immunohistochemistry,Western Blot,
免疫原
Anti-Periostin Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the fasciclin domain 1 of mouse periostin.
来源宿主
Rabbit
反应性
Gallus gallus (Chicken); H. sapiens (Human); Mus musculus (Mouse)
保存建议
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
