Interferon alpha Receptor Type I pS535/pS539 Antibody detects Interferon alpha Receptor Type I phopshorylated at positions S535/S539. Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon-α Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1. Therefore, Interferon alpha Receptor Type I phospho S535/phospho S539 antibody is ideal for investigators involved in Cell Signaling, Virology, Immunology and Cancer Research.
应用类型
Immunohistochemistry,Western Blot,
免疫原
Anti-Interferon alpha Receptor Type I pS535/pS539 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser535/539.
来源宿主
Rabbit
反应性
H. sapiens (Human)
保存建议
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
