- 中文名称
【干冰】Anti-Collagen I, alpha 1 telopeptide (Rabbit) Antibody - 600-401-D20
- 英文名字
- 【干冰】Anti-Collagen I, alpha 1 telopeptide (Rabbit) Antibody - 600-401-D20
- 供应商
- Rockland
- 产品货号
- 600-401-D20
- 产品报价
- ¥询价/100uL

- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻

- 背景资料
- Collagen I alpha 1 telopeptide Antibody detects collagen I which is an extracellular matrix protein that serves as a scaffold defining the shape and mechanical properties of many tissues and organs including skin, tendon, artery walls, fibrocartilage, bone and teeth. Type 1 collagen is the most abundant protein in mammals. Collagens are synthesized with N-terminal and C-terminal propeptides that are cleaved during maturation and secretion. After cleavage of the propeptides, the most N-terminal and C-terminal remaining sequences are known as telopeptides. Mutations in the collagen 1, alpha 1 gene (COL1A1) are known to cause osteogenesis imperfecta (aka brittle bone disease). Furthermore, mutations found in the first 90 residues of the helical region of alpha 1 collagen have been implicated in the prevention or delayed removal of the procollagen N-propeptide leading to a combined osteogenesis imperfecta and Ehlers-Danlos syndrome (EDS) phenotype. Anti-Collagen I alpha 1 telopeptide Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
- 应用类型
- ELISA,Immunohistochemistry,Immunoprecipitation,Western Blot,
- 免疫原
- Anti-Collagen-1 alpha 1 telopeptide Antibody was produced in rabbit by repeated immunizations with a proprietary peptide immunogen corresponding to collagen-1 alpha 1 telopeptide (C-terminal region).
- 来源宿主
- Rabbit
- 反应性
- H. sapiens (Human); Mus musculus (Mouse); Ovis aries (Sheep); Rattus (Rat)
- 保存建议
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- 其他
- Rockland成立于1962年,是一家老牌抗体原产企业,其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体,包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素(Ubiquitin)等识别抗体,应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外,Rockland也生产特别齐全的二抗,包括纯化、生物素、HRP/ALP、荧光标记二抗,应用十分广泛。

- 注意
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