MART-1 (also known as Melan-A) is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1,Tyrosinase,gp100,gp75,BAGE-1,and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. Recombinant human MART-1 (Cat.# 4823-5) can be used as a positive control.
免疫原
E. coli expressed recombinant human MART-1
来源宿主
兔
反应性
经检测验证,可与人种属来源的MART-1蛋白发生免疫反应.
保存建议
提供的MART-1抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该MART-1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.