The Trefoil Factor peptides (TFF1,TFF2 and TFF3) are expressed in the gastrointestinal tract,and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma. Human TFF2 is a 12.0 kDa polypeptide of 106 amino acid residues.
应用类型
Western blot analysis (0.5-2 ug/ml). Per researchers feedback, it can also be used in ELISA (2-3 ug/ml) and neutralization (3-6 ug/ml). However, the optimal conditions should be determined individually.
免疫原
E. coli expressed human TFF-2
来源宿主
兔
反应性
经检测验证,可与人种属来源的TFF-2/Spasmolysin蛋白发生免疫反应.
保存建议
提供的TFF-2/Spasmolysin抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该TFF-2/Spasmolysin抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.