Human IGF-BP1 is a cysteine-rich secreted protein expressed in liver，decidual，and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions，whereas nonphosphorylated IGF-BP1 is stimulatory.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Recombinant human IGFBP-1 （Cat.# 4717-25） can be used as a positive control. Other applications have not been determined.
免疫原
E. coli expressed human IGF-BP1 （Cat.# 4717-25）
来源宿主
兔
反应性
经检测验证，可与人种属来源的IGF-BP1蛋白发生免疫反应.
保存建议
提供的IGF-BP1抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该IGF-BP1抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
