Follistatin belongs to a group of structurally-diverse diffusible proteins that binds to TGF-beta ligands and inhibit their activity by hindering access to signaling receptors. This naturally occurring antagonist binds to Activin,BMP-2,-4,-6,-7,Myostatin,GDF-11,and TGF-beta1. Follistatin is expressed in the pituitary,ovaries,decidual cells of the endometrium,and in some other tissues. Human Follistatin is a 31.5 kDa protein containing 288 amino acids.
应用类型
Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
E. coli expressed human Follistatin
来源宿主
兔
反应性
经检测验证,可与人种属来源的Follistatin蛋白发生免疫反应.
保存建议
提供的Follistatin抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该Follistatin抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.