Lectins are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes,including embryogenesis,inflammatory responses,cell progression and metastasis. Galectin-3 can function intracellularly in controlling cell cycle and preventing T-cell apoptosis,and also extracellularly,in activating various cells,including monocytes/macrophages,mast cells,neutrophils,and lymphocytes. Human Galectin-3 is a globular 26.0 kDa protein containing 250 amino acid residues.
应用类型
Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
E. coli expressed human Galetin-3
来源宿主
兔
反应性
经检测验证,可与人种属来源的Galectin-3蛋白发生免疫反应.
保存建议
提供的Galectin-3抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该Galectin-3抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.