BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name,BMPs initiate,promote and regulate bone development,growth,remodeling and repair. BMP-5 has been indicated to induce cartilage formation.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 29 of human BMP-5
来源宿主
兔
反应性
经检测验证,可与人、小鼠种属来源的BMP-5蛋白发生免疫反应.
保存建议
提供的BMP-5抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该BMP-5抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.