BMPs （bone morphogenetic proteins） belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name，BMPs initiate，promote and regulate bone development，growth，remodeling and repair. In vivo studies have shown that BMP-3 can independently induce cartilage formation.
应用类型
Western blotting （0.5-4 ug/ml）. It detects the ~55 kDa full length and the ~16 kDa cleaved fragment of BMP-3. Blocking peptide （Cat.# 5673RBP-50） is available separately.
免疫原
Synthetic peptide surrounding amino acid 369 of mouse BMP-3
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的BMP-3蛋白发生免疫反应.
保存建议
提供的BMP-3抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该BMP-3抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
