BMPs （bone morphogenetic proteins） belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name，BMPs initiate，promote and regulate bone development，growth，remodeling and repair. In addition to its osteogenic activity，BMP-2 plays an important role in cardiac morphogenesis. It is also expressed in a variety of tissues such as lung，spleen，brain，liver，prostate ovary and small intestine.
应用类型
Western blotting （0.5-2 ug/ml）. It detects the 14 kDa monomer， 28 kDa dimer， as well as the 58 kDa tetramer of human BMP-2. Recombinant human BMP-2 （Cat.# 4577-10） can be used as a positive control. Reactivity to other species has not been tested.
免疫原
Recombinant human BMP-2
来源宿主
兔
反应性
经检测验证，可与人种属来源的BMP-2蛋白发生免疫反应.
保存建议
提供的BMP-2抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该BMP-2抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
