RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ （found in inflammatory zone） and RELM. The three known members of this family； Resistin，RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha are still unknown. Murine RELM-alpha is a 10.0 kDa monomeric protein containing 88 amino acid residues.
应用类型
Western blot analysis （0.5-4 ug/ml）. Recombinant murine RELM （Cat.# 4631-20） can be used as a positive control. However， the optimal conditions should be determined individually.
免疫原
E. coli expressed recombinant murine RELM
来源宿主
兔
反应性
经检测验证，可与小鼠种属来源的RELM-alpha蛋白发生免疫反应.
保存建议
提供的RELM-alpha抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该RELM-alpha抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
