BMPs (bone morphogenetic proteins) belong to the TGF-B superfamily of structurally related signaling proteins. As implied by their name，BMPs promote and regulate bone development，growth，remodeling and repair，in both prenatal development and postnatal growth of eye，heart，kidney，skin，and other tissues. BMP-10 is essential for the proper development of the heart，but is not expressed until after cardiac patterning or looping is completed.
