PAI-1 （plasminogen activator inhibitor-1） is originally cloned from human endothelial cell and rat hepatoma cell cDNA libraries. As a member of the serpin family of serine protease inhibitors，PAI-1 inhibits both tissue-type palsminogen activator （t-PA） and urokinase-type plasminogen activator （u-PA）. High PAI-1 levels are associated with an increased risk of thromboembolic disease while PAI-1 deficiency may represent an inherited autosomal recessive bleeding disorder.
应用类型
Western blot analysis （1-2 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects rat PAI-1. Cross reactivity of the antibody to other species has not been determined.
免疫原
Recombinant rat PAI-1
来源宿主
兔
反应性
经检测验证，可与大鼠种属来源的PAI-1蛋白发生免疫反应.
保存建议
提供的PAI-1抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有50%甘油， 0.1% BSA， 0.02%硫柳汞的PBS （pH 7.2）缓冲液中.请将该PAI-1抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
