RANTES （regulated upon activation，normal T-cell expressed and secreted） is a 70-amino acid CC chemokine originally cloned from T-cell-specific sequences-enriched cDNA libraries. Both human and murine RANTES are chemotactic for monocytes. Human RANTES is also a chemoattractant for T-cells and eosinophils，as well as an activator of basophils for histamine release. In contrast to other CC chemokines，RANTES is only slowly expressed after activation of leukocytes. It is involved in a number of pathological conditions like chronic inflammation and autoimmune diseases.
应用类型
Western blot analysis （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. RAW264.7 cells treated with LPS （15 hr） can be used as a positive control.
免疫原
E. coli-expressed mature rat RANTES （a.a. 1-70）
来源宿主
兔
反应性
经检测验证，可与小鼠、大鼠种属来源的RANTES蛋白发生免疫反应.
保存建议
提供的RANTES抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有50%甘油， 1% BSA， 0.02%硫柳汞的PBS （pH 7.2）缓冲液中.请将该RANTES抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
