The myelin transcription factor 1 family，to which the myelin transcription factor 1-like protein （MYT1L） belongs，is expressed primarily in the developing central nervous system and recruits histone deacetylase （HDAC） to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B，a protein that mediates transcriptional repression by binding to HDACs，suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.
应用类型
Western Blot: 1 - 2 ug/ml， ELISA. However， the optimal conditions should be determined individually.
免疫原
Rabbit polyclonal MYT1L antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MYT1L.
