Growth differentiation factors （GDFs） are members of the transforming growth factor （TGF） superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development，with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal，another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.
应用类型
Western Blot: 1 - 2 ug/ml， ELISA. However， the optimal conditions should be determined individually.
免疫原
Rabbit polyclonal GDF1 antibody was raised against a 16 amino acid peptide near the amino terminus of human GDF1.
