The Epilepsy,progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate,suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
应用类型
Western Blot: 1 - 2 ug/ml, ELISA. However, the optimal conditions should be determined individually.
免疫原
EPM2A antibody was raised against a 17 amino acid peptide near the carboxy terminus of human EPM2A.