KC,a homolog of human and hamster gro/MGSA,is a 72-amino acid CXC chemokine originally cloned from rat macrophages and lung tissue. It is the mediator for recruitment and activation of netrophils in rat lung inflammation models. Expression of KC can be upregulated by LPS and IL-1B stimulation. IFN-g blocks LPS-induced expression of KC.
应用类型
Western blot analysis (0.5-4 ug/ml), Immunoprecipitation (3-5 ug/ml), and Immunohistochemistry (10-20 ug/ml). However, the optimal conditions should be determined individually.
免疫原
E. coli-expressed rat KC
来源宿主
兔
反应性
经检测验证,可与小鼠、大鼠种属来源的KC蛋白发生免疫反应.
保存建议
提供的KC抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有50%甘油, 1% BSA, 0.02%硫柳汞的PBS (pH 7.2)缓冲液中.请将该KC抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.