IP-10 (interferon-gamma induced protein 10 kDa; in mouse also called cytokine responsive gene 2,Crg-2,or mob-1) is a highly inducible,primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. Like Mig,IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes,natural killer and T-cell migration,regulation of T-cell and bone marrow progenitor maturation,modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor,CXCR3.
应用类型
Western blot analysis (0.5-2 ug/ml). However, the optimal conditions should be determined individually.
免疫原
E. coli-expressed recombinant rat IP-10
来源宿主
兔
反应性
经检测验证,可与大鼠种属来源的IP-10蛋白发生免疫反应.
保存建议
提供的IP-10抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有50%甘油, 1% BSA, 0.02%硫柳汞的PBS (pH 7.2)缓冲液中.请将该IP-10抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.