IL-15 is a member of the four alpha-helical bundle family of cytokines with a molecular weight of 14-15 kDa. Its in vitro activity is very similar to IL-2,except that IL-15 utilizes the IL-15 receptor alpha subunit for binding. IL-15 plays an important role in the growth and differentiation of T and B lymphocytes,natural killer cells,macrophages,and monocytes. It also activates a number of important intracellular signaling molecules. This implies that IL-15 could be essential for the immune responses,allograpt rejection,and the pathogenesis of autoimmune diseases.
应用类型
Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
E. coli-expressed mouse IL-15
来源宿主
兔
反应性
经检测验证,可与小鼠种属来源的IL-15蛋白发生免疫反应.
保存建议
提供的IL-15抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有50%甘油, 1% BSA, 0.02%硫柳汞的PBS (pH 7.2)缓冲液中.请将该IL-15抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.