Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines，including IL-4，IL-5 and IL-13，and exerts multiple inflammation related bioactivities.
应用类型
1） WB: Use 0.1-0.2 ug/ml. The detection limit for recombinant human IL-33 is 1.5-3.0 ng/lane， under either reducing or non-reducing conditions. 2） ELISA: Use 0.5 - 2.0 ug/ml （100 ul/well antibody solution） 3） Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of Human IL-33 （1.0 ng/ml）， a concentration of 0.2-0.4 ug/ml of this antibody is required. 4） Immunohistochemistry: 0.125 ug/ml-0.25 ug/ml with an overnight incubation at 4°C
