- 中文名称
【奥托拉普林】再生人内耳纤维细胞源性蛋白（1 mg）
- 英文名字
- Otoraplin (OTOR), human recombinant
- 供应商
- Biovision
- 产品货号
- 4987-1000
- 产品报价
- ￥已停产
- 产品说明书
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- 产品新闻
- 背景资料
- TOR proteins is also known as fibrocyte-derived protein (Fdp) and Melanoma inhibitory activity-like (MIAL). Otoraplin is a member of the melanoma-inhibiting activity gene family. Otoraplin is a secreted 16 kDa globular protein that is expressed in the inner ear by periotic mesenchyme and developing and mature fibrocytes. OTOR is highly homologous to MIA/cartilage-derived retinoic acid-sensitive protein (CD-RAP), which is a cartilage-specific protein that is also expressed in malignant melanoma cells. The 111 amino acid mature human otoraplin contains 1 SH3 domain (46 –107 amino acids) and a Tyr at position 50 that is reportedly sulfated. Otoraplin takes part in the initiation of periotic mesenchyme chondrogenesis. Otoraplin is secreted through the Golgi apparatus and plays a role in cartilage development and maintenance. A frequent polymorphism in the translation start codon of OTOR can abolish translation and may be associated with forms of deafness. Recombinant human Otoraplin produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 111 amino acids and having a molecular mass of 12.7 kDa.The OTOR is purified by proprietary chromatographic techniques.
- 序列
- 重组人内耳纤维细胞源性蛋白蛋白产品，又称Otoraplin, Fibrocyte-derived protein, Melanoma inhibitory activity-like protein, OTOR, MIAL, FDP, MIAL1, MGC126737, MGC126739, .其对应NCBI基因号为4282，NCBI基因别称为MIF；该基因种属来源为人源，对应Accession号为P14174 .该蛋白产品又称等.
- 来源宿主
- 提供的【Otoraplin】重组人内耳纤维细胞源性蛋白产品的来源为大肠杆菌中重组表达.
- 溶解建议
- 提供的重组人内耳纤维细胞源性蛋白 产品为冻干粉末建议将其重新溶解于无菌纯水至浓度为0.1 -1 mg/ml，后继实验可根据实验要求使用合适的水溶液进一步稀释.
- 保存建议
- 在您收到艾美捷发出的【Otoraplin】重组人内耳纤维细胞源性蛋白产品后，建议将其置于-20°C保存.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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