MIA2 performs as a tumour suppressor in hepatocellular carcinoma. MIA2 is a novel acute phase protein which its expression is found in the liver and reacts to liver damage in chronic liver diseases and is considerably higher in severe fibrosis patients . MIA2 is induced by IL6, TGF- and conditioned medium from activated hepatic stellate cells. MIA2 is is mainly expressed in hepatocytes. MIA2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain consisting of 101 amino having a total molecular mass of 11.5 kDa. The MIA2 is purified by proprietary chromatographic techniques.
序列
重组人MIA-2蛋白产品,又称Melanoma inhibitory activity protein 2, Melanoma inhibitory activity protein 2.其对应NCBI基因号为117153,对应Accession号为Q96PC5.
来源宿主
提供的【MIA 2】重组人MIA-2产品的来源为大肠杆菌重组表达.
溶解建议
重组人MIA-2产品请按照说明书建议进行溶解操作:Reconstitute in sterile H₂O at >100 ug/ml. Reconstituted MIA2 should be stored in working aliquots at -20°C. .