Tuberous sclerosis complex （TSC） is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin （TOR），an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors
应用类型
The antibody can be used for Western blotting （1–4 ug/ml）.
免疫原
Synthetic peptide surrounding amino acid 1075 of mouse TSC1
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的TSC1蛋白发生免疫反应
保存建议
提供的200 ug TSC1抗体产品为无色溶液其浓度为0.5mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该TSC1抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
